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At the 1 He concluded by noting a draft statement from the upcoming European Society for Medical Oncology (ESMO) guidelines

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Cysteine, unlike most other amino acids, is extremely unstable and rapidly autoxidizes to cystine which is the oxidized disulphide form

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The machinery for oxidative protein folding in the IMS is an obvious candidate for such a crosstalk since it has previously been shown that at least in vitro GSH increases the efficiency of target protein oxidation (Bien et al , 2010)