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Martin JL, Avkiran M, Quinlan RA, Cohen P, Marber MS: Antiischemic effects of SB203580 are mediated through the inhibition of p38alpha mitogen-activated protein kinase: Evidence from ectopic expression of an inhibition-resistant kinase

May reduce frequency of episodes over time

This is working well for me

Nausea is a very common side effect when starting AOM however a minority of patients are very sensitive to AOM and even the starting dose can result in them having severe nausea and difficulty eating anything or even drinking water, risking dehydration and kidney injury

The application of this peptide is not just theoretical

As GLP-1 agonists can help reduce inflammation and consequent pain (two side effects of extreme adiposity and of lipedema), ozempic, wegovy, mounjaro etc can be helpful in that way