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Key sleep factors: consistent bedtime within a 30-minute window, dark room (blackout curtains or sleep mask), no screens 60 minutes before bed, room temperature between 65 and 68 degrees Fahrenheit, and no alcohol within 3 hours of sleep

This dual action can slow multiple signs of aging, from fine lines to joint aches

J Pediatr 175:206210

However, like all treatments, they can have side effects, particularly if administered improperly or in excessive amounts

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GLP-1RA activate the cAMP/PKA pathway leading to phosphorylation of sodium-hydrogen exchanger 3 (NHE3) in renal proximal tubular cells, increasing natriuresis and diuresis and lowering blood pressure