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Monitoring focuses on broad health markers, with copper-specific labs reserved for repeated or higher systemic exposure contexts

Patients may not regard these products as medicines

We ignore other reactive oxygen species besides H 2 O 2 , or, put a different way, H 2 O 2 represents them all

Treatment recommendations are based on provider evaluation

Of note, hemolysis is a fundamental feature of SCD and resulting excess hemin exposure 32 while hypoxia has been shown to induce the expression of fetal hemoglobin 33,34 , and promote the transition from expansion to differentiation during stress erythropoiesis 35

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