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9 Conclusion This review provides a comprehensive overview of the mechanisms underlying liver detoxification and its central role within the gutliverhypothalamus axis

ChaC2 is on chromosome 2p16.2 and encodes a protein with 184 amino acid residues and a molecular weight of ~20.9 kDa (20,47,50)

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Its strong antioxidant properties shield skin cells from oxidative stress, which can worsen inflammation, by helping neutralise free radicals

Texture: The skin affected by melasma feels smooth and normal to the touch

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