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Wang et al., 2020a)

Units change because the concentration changes depending on how much diluent is added to the vial

Blood levels rise across the first several weekly doses and settle near steady state after about four weeks. That is why the four-week hold matters: the full effect of a dose change is not visible in the first few days

Drug working concentrations and stock preparation were as follows: GLP-1MK-801 and MK-801 (both 50 M, dissolved in aCSF or magnesium-free aCSF), NMDA (100 M, dissolved in magnesium free aCSF), CNQX (10 M, dissolved in DMSO, Alomone Labs), picrotoxin (100 M, dissolved in DMSO)

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Birben E, Sahiner UM, Sackesen C, Erzurum S, Kalayci O