There was a randomised six-month trial where glutathione in its oral form (at 250 mg and 1000 mg) increased stores in a measurable, time-dependent relationship
Side Effects & Safety Nausea 44% in STEP trials, most common side effect, dose-dependent Diarrhea 30% in trials Vomiting 24% in trials Constipation 24% in trials Stomach pain 20% in trials Pancreatitis rare but documented
It can express transcription factors Mac1 and Ctr1, which promote copper absorption, and can also avoid toxic effects caused by excessive copper accumulation through its unique plasma membrane structure and the activation of the copper resistance assay gene CRD1 [41,42,43,44,45]
Dlling M, Eckstein M, Singh J, et al
A peptide calculator can help simplify this process
Sci Rep 9 , 5360 (2019)