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Results take longer to appear but compliance is significantly higher because people do not quit from unbearable side effects
Those who received the GLP-1 infusion were found to consume 12 percent fewer calories than those hooked up to just saline (Flint, Raben, Astrup)
Balguid A, et al
However, without the ongoing prebiotic input, bacterial populations will gradually shift back toward their pre-supplement state, and any appetite-modulating effects will fade accordingly
These claims have not been independently verified
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