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In one example, GSH-driven nanoparticle disintegration releases indomethacin to inhibit PTGS2 while reducing Pt 4 + to cytotoxic Pt 2 + , thereby amplifying cisplatin-induced pyroptosis in pancreatic cancer 218

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Sakamoto T, Higaki Y, Hara M, Ichiba M, Horita M, Mizuta T, et al

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