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Consequently, these observations have sparked renewed discussions about the therapeutic potential of GIPRAs in the long-term treatment of obesity

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Practical tip A combination of SGLT2i and GLP-1RA might theoretically improve cardiorenal benefits in patients with T2D and either ASCVD or multiple risk factors for ASCVD whose A1c remains suboptimal despite initial treatment with only one of these agents or if clinical status changes (e.g., new onset HF or CKD

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27 , 461469.e6 (2018)

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If you need escalating further, then up to 1mg

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