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A 2026 study published in The Lancet found a similar pattern with tirzepatide in a similar cohort of postmenopausal women

The medication restores appetite regulation that estrogen previously helped maintain, explaining why many menopausal women experience particularly dramatic improvements in hunger control

doi: 10.1007/s00213-008-1196-6 79

However, serum B12 is a crude measure and can be normal even in the presence of functional deficiency

The question in this articles title looks simple, but it actually stitches together two very different claims that are worth separating before we do anything else

The question is whether the full development package supports approval for the proposed use and label