"Mitochondrial Respiration and NNMT Expression in Aged Skeletal Muscle." MDPI Pharmaceutics (2026)
It was added to the Prohibited List in 2022 as a non-approved substance, reflecting its transition from an obscure research compound to a significant "substance of interest" in professional athletics
It will likely include guidance on focusing on high-protein, high-fiber meals, increasing physical activity, and making other lifestyle adjustments
Originally developed to treat Type 2 Diabetes, GLP-1s have proven to be highly effective, albeit very expensive, when prescribed for weight loss
Inhibition of xCT by Class 1 ferroptosis inducers, such as erastin, may induce ferroptotic cell death mainly by depletion of cellular GSH content, and subsequently lead to inactivation of glutathione peroxidase-4 (GPX4
The current evidence is promising but incomplete