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Until the 1920s, there was no treatment for PA and people did die young after many years of illness

Many opt to take supplemental B12 alongside a folate supplement to avoid this risk (23, 24)

Medication-induced deficiency: Long-term use of certain medications, such as proton pump inhibitors (PPIs) and metformin, can interfere with vitamin B12 absorption and contribute to deficiency

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Weight fluctuates daily due to water retention, food volume, and hormonal cycles, so weekly averages provide better data than daily numbers

To control it, inject a small amount of air into the vial first (about 0.5 mL) through the needle before adding water