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Saudi J Bio Sci 29:11971209
Differential Metabotypes in Synovial Fibroblasts and Synovial Fluid in Hip Osteoarthritis Patients Support Inflammatory Responses
74 RA also influences the brain by causing fatigue and reduced cognitive function
Kidney problems Severe vomiting or diarrhea can lead to dehydration
For instance, rapid weight loss can lead to fluctuations in estrogen levels, gut and vaginal flora, or pelvic muscle tone, which may explain symptoms like dryness, discharge changes, or infections
Keywords : Phospholipase C, cancer development, intracellular signaling, oncogene, tumor suppressor Phospholipase C (PLC) family, consisting of 6 subgroups - PLC, , , , , , is a group of proteins able to hydrolyze membrane phosphoinositol 4,5-bisphosphates (PIP2) to inositol-1,4,5-phosphate (IP3) and diacylglycerol (DAG) - both important second messengers - in response to extracellular stimuli including hormones and growth factors through activation of the different receptor tyrosine kinases (RTK) or G-protein-coupled receptors (GPCR) [1]
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