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Who Should Not Use Retatrutide Retatrutide may not be appropriate for individuals with certain medical conditions, including: Personal or family history of medullary thyroid carcinoma (MTC) Multiple endocrine neoplasia type 2 (MEN2) History of pancreatitis Uncontrolled or unstable medical conditions Endocrine disorders requiring specialist evaluation All patients should undergo physician assessment before considering treatment

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Aug 1 2021;147(8):708-716