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Therefore, they rely on protecting antioxidant substances synthesized and secreted by epididymal epithelial cells, including glutathione peroxidase 5 (GPX5) (Taylor et al., 2013)
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Critical roles in maintaining redox are exerted by antioxidant systems, including the thioredoxin/peroxiredoxin systems and the nuclear erythroid related transcription factor 2 (Nrf2), which regulates the expression of detoxification proteins such as Kelch-like ECH-associated protein 1 (Keap1) [181]
Both target dark spots
Circulation 94 : 18121814
Chemokine and Chemokine Receptor Expression in Paired Peripheral Blood Mononuclear Cells and Synovial Tissue of Patients With Rheumatoid Arthritis, Osteoarthritis, and Reactive Arthritis
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