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In addition, questions remain about the impact of GLP-1R signaling on immune cell biology and the precise role of GLP-1RAs in various autoimmune and autoinflammatory conditions
Observed outcomes include specific cellular and molecular endpoints such as: Enhanced fibroblast migration capacity Increased collagen and elastin deposition Modulation of pro-inflammatory and antioxidant mediators Altered transcriptional profiles related to tissue homeostasis, repair signaling, and stress response All reported observations derive exclusively from preclinical laboratory and animal studies and remain model-specific
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