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A drug can move a fluid biomarker in the apparently favourable direction and still fail the patient

Cell 130 , 10951107 (2007)

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Laboratory and animal studies suggest GLP-1 receptor agonists may also inhibit nuclear factor-kappa B (NF-B) signaling, a key pathway in inflammatory gene expression, and reduce oxidative stress through enhanced antioxidant enzyme activity

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For example, is it pure liposomal glutathione, or is it a combination supplement with a super high dose of B12 that has been shown to impair sleep in some individuals