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Proc Natl Acad Sci U S A 106(31):1305213057
Hind-Limb Ischemia Model In a rat femoral artery ligation model (a standard peripheral-artery-disease analog), BPC-157 at 10 mcg/kg/day for 10 days increased collateral vessel density by approximately 35% compared to controls, measured by latex cast perfusion imaging
Targeting a 250 mcg dose: To administer 250 mcg, draw the solution to the 10-unit mark on the syringe (10 units x 25 mcg/unit = 250 mcg)
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The FDA will make the final decision, and it's important to remember that these peptides remain unapproved by the FDA, with ongoing questions about their safety and effectiveness
The skin should be kept clean with continued application of ointment as directed
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