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doi:10.4049/jimmunol.1801180

[21] A randomized, double-blind, placebo-controlled study on oral glutathione supplementation (500 mg twice daily for four weeks) in 40 healthy adult volunteers failed to show any significant change in serum glutathione levels

It encourages the differentiation of macrophages into pro-fibrotic M2 phenotypes and an increase in extracellular matrix synthesis, which exacerbates renal fibrosis

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