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WellPoints argument was straightforward: these drugs have safety profiles that make self-administration entirely appropriate for the general population, and their prescription-only status was generating hundreds of millions of dollars in unnecessary prescription drug spending that payers were absorbing through formulary coverage

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Those with severe hepatic impairment should avoid this medication due to insufficient safety data

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2022a, b, c) SARS-CoV-2-induced OS activates activation of different signaling pathways, which counterbalances this type of complication