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GLP-1: from lizard venom to modern medicine One of the most fascinating origin stories in pharmacology

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Glutathione: dehydroascorbate oxidoreductases [PMID: 7476366] Laboratory literature summary: Glutathione: dehydroascorbate oxidoreductases

People with severe gastrointestinal (GI) disorders, such as gastroparesis or inflammatory bowel disease, should also avoid GLP-1 agonists due to the possibility of exacerbating GI symptoms (23)

Nat Commun 3:814 Lscher C (2013) Cocaine-evoked synaptic plasticity of excitatory transmission in the ventral tegmental area

It serves as a cornerstone of the FDAs post-marketing safety surveillance initiative for pharmaceuticals and therapeutic agents, operating as a classic spontaneous reporting system