In diet-induced obese (DIO) mouse models, NNMT inhibition with 5-Amino-1MQ was associated with reduced white adipose tissue mass without affecting food intake, suggesting changes in energy expenditure rather than appetite suppression
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(Z)-Tamoxifen
GST enzymes catalyze the chemical binding of glutathione's sulfur group directly to electrophilic toxins, including heavy metals, alcohol metabolites, and drug byproducts
No long-term hard-outcome data
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