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36 The high recurrence rate (13%26%) of this largely blind procedure is the reason to use the technique with caution
Whilst gastrointestinal side effects such as nausea and diarrhoea are well-recognised, some patients report joint pain during treatment
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These findings indicate that GDF8 and ActA are key regulators of muscle loss during caloric restriction, and that blocking these negative regulators of muscle mass during the treatment of obesity with GLP-1 RAs could provide profound and wide-ranging benefits
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