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Mol Clin Oncol

10.1007/s00210-010-0559-9 50 LaiT.TsaiY.LiouC.FanC.HouY.YaoT.et al (2024)

Tirzepatide is a synthetic peptide medication derived from the structure of human gastric inhibitory polypeptide (GIP), engineered to activate both GIP and glucagon-like peptide-1 (GLP-1) receptors

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Endpoints included area under the semaglutide plasma concentrationtime curve during a 24-h interval after the 10th dose ( AUC 024h ) (primary endpoint) and maximum observed semaglutide plasma concentration after the 10th dose ( C max ) (secondary endpoint)

R.SmallJ.O'ConnellR.TalbottG.AltonG.ZapfJ