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In the STEP and SURMOUNT trials, mood-related side effects occurred in less than 2% of participants, often indistinguishable from placebo rates
Additional information Jingfeng Wang: Senior author
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How is works: GLP-1 receptor: satiety signalling and slower gastric emptying GIP receptor: post-prandial insulin response and fat metabolism Practical logistics so your work isnt waiting on a parcel Glucagon receptor: promotes energy expenditure and fat mobilisation The combined pathway engagement is being investigated for additive or synergistic effects across these systems
But there is a risk that people start seeing this drug as a quick weight-loss strategy, Rubino said
C, Godar, S
