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No, they are very different

Combining payloads with different mechanisms of action may also overcome resistance: for example, preclinical studies of an ADC carrying both TOPI and tubulin inhibitor payloads have demonstrated potent antitumor activity in TOPI inhibitor-resistant tumors 236

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These reactions are typically temporary and resolve on their own within a few days

First, because the KNHANES is a cross-sectional survey, this study can confirm the association but cannot establish a causal relationship