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It is noteworthy that the effects of BCAAs on insulin sensitivity exhibit a concentration-dependent pattern: beneficial at physiological levels but deleterious at pathological concentrations (14, 22)
A 2021 meta-analysis in Obesity Reviews examining probiotic supplementation for weight management found small effectstypically 0.5 to 2 kg greater weight loss compared to placebo over 8-12 weeks
Shimizu, T
While this mechanism contributes to weight loss and glycemic control, it can produce gastrointestinal symptoms and affect other aspects of patient care
PLoS One 10:e0119479
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