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The main mechanism of ferroptosis Inhibiting the cysteine-glutamate transporter system Xc can induce ferroptosis System Xc is a sodium independent antiporter that export intracellular glutamate and import extracellular cystine across the membrane in a ratio of 1:1 to synthesize glutathione in cells [19]

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The GLP1R gene encodes the very receptor semaglutide activates, while FTO , MC4R , and TCF7L2 influence fat mass, satiety, and glucose regulation

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