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Diabetes Surveillance System also shows elevated rates of diagnosed diabetes throughout both states, including many counties in Southeast Ohio and Southern West Virginia
In a randomized trial of semaglutide 2.4 mg vs placebo for 1 year, 529 participants with HFpEF with a BMI of 30 kg/m2, there was a very large reduction in symptoms, improvement in exercise function in the GLP-1 drug assigned group
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14.2 Weight Reduction and Long-term Maintenance Studies in Adults with Obesity or Overweight SPL UNCLASSIFIED SECTION Overview of Clinical Trials in Adults The efficacy of WEGOVY once weekly subcutaneous injection for weight reduction and long-term maintenance of body weight in conjunction with a reduced-calorie diet and increased physical activity were studied in three 68-week, randomized, double-blind, placebo-controlled trials
The other switched to placebo, effectively stopping the medication
Adjustments to medication doses may be necessary to optimize therapeutic outcomes and minimize side effects
