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Flow cytometry was conducted with the support of the Flow Cytometry Core Facility of the CMCB Technology Platform and the FACS Facility of the Institute for Physiological Chemistry, both at the Technische Universitt Dresden

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GAD67 is encoded by the GAD1 gene and expressed in the neuronal soma or throughout the entire neuron, whereas GAD65 is encoded by the GAD2 gene and expressed at axon terminals

METAOD005: A Phase IIb (randomized, double-blind, placebo-controlled) study to assess the efficacy (reduction in body weight), safety and tolerability of 12 weeks treatment with daily doses (1, 5, 10, 20 or 30 mg AOD9604) administered orally (capsules) in 300 healthy, clinically obese males, and females of non-child bearing potential, with a BMI 35 kg/m 2

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