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Reported to act on fat-cell metabolism without stimulating IGF-1 production, distinguishing it from full GH in preclinical work

Modulation of Hormones DSIP has been linked to increased production of growth hormone (GH) during sleep and may suppress corticotropin (ACTH) and cortisol , aligning with its stress-relieving effects

Mittler et al., 2004)

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Enemas can, however, promote weight loss through their laxative effect

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