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Martn-Rufin M, Nascimento-Gomes R, Higuero A, Crisma AR, Campos-Sandoval JA, Gmez-Garca MC, et al

Native rhIGF-1 (mecasermin / Increlex) is FDA-approved for severe primary IGF-1 deficiency

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Gingival epithelial cells were microscopically separated, minced, and digested at 37 C for 10 minutes

There is also no strong efficacy argument for rushing: in REDEFINE 2 only 61.9% of patients were on the full 2.4 mg at the end of the trial and the group still averaged 13.7%

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