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Jensen et al., 2018) while a low level of GLP-1R-immunoreactivity was revealed in rat hippocampus ( in vivo electrophysiological recordings showed that juxtacellular application of the active fragment of GLP-1, GLP-1 (736) amide induces an increase and then a decrease of firing activity in the hippocampal CA1 neurons

it is essentially "spent." Oxidized glutathione (GSSG) occurs when two spent glutathione molecules bind together for stability