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The E3 ubiquitin ligases MuRF1 and MAFbx/atrogin-1 serve key roles in skeletal muscle degradation (70)
However, it is essential to note that when additional pharmacological intervention is required to control diabetes mellitus, the choice between SGLT-2 inhibitors and GLP-1 RAs should be based on the patients individual needs and the specific medications already being used
CS has been implicated in several cardiovascular diseases, liver diseases as well cancer [8, 9]
GLP-1 medications reduce the emotional salience of food - the comfort, reward and anxiety-relief functions that food served before treatment
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