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Coskun 2022 mmc3 Table 3 + mmc1 Table S8 Phase 1 single-ascending-dose study (NCT03841630, n=45, conducted in Singapore)

Repeat testing at 4-8 weeks helps assess individual response and tolerability before dose adjustment

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Consider seeking referral to a specialist if you experience persistent pain despite first-line therapy, infertility after 6-12 months of attempting conception (earlier if age 35), abnormal imaging findings (such as endometriomas), or recurrent emergency department visits