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PMID 31316992

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This distal tubular condition is perceived as a low effective circulating volume stimulus, at the level of juxtaglomerular apparatus, which promotes the inhibition of adenosine production that is associated with a vasodilatory response of the afferent arteriole (33)

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After allowing tumours to develop in these mice, the tumours were excised and orthotopically implanted into recipient immunocompetent wild-type (WT) mice (C57BL/6)

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