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Glutathione from antioxidant to post-translational modifier
By inhibiting Gwt1, Fosmanogepix disrupts the anchoring of mannoproteins on the fungal surface, impairing growth and pathogenicity through a mechanism distinct from azoles and echinocandins, thereby reducing the likelihood of cross-resistance (Pappas et al., 2023)
Existing products largely fail to meet the need for dense, nutrient-rich foods that appeal to diminished appetites
2011;6(8):e23788
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Compared with placebo, the extract group ate less: daily energy intake was about 748 kJ lower at week 12 and 545 kJ lower at week 24, and reductions in hunger and cravings reached significance at multiple points across the study [4]
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