Deficiencies in thyroid, gonadal, adrenal or growth hormone axes are addressed according to the pattern
At the same time, compared to HCs, the levels of a wide range of metabolites such as glutamine, asparagine, N-Formimino-glutamate, putrescine, serotonin, kynurenine, 2-Aminomuconate, Cys-Gly, 5-Aminolevulinate, and pyridoxine were reduced in the plasma of R group ( Figure 5C , Supplementary Figure 4A )
(2014) Metformin improves glucose effectiveness, not insulin sensitivity: predicting treatment response in women with polycystic ovary syndrome in an openlabel, interventional study
Extreme weather
References: Charbonnel B, Cariou B (2011): Pharmacological management of type 2 diabetes: the potential of incretin-based therapies
A key hypothesis we are studying here is that in endometriosis, a pro-oxidant microenvironment in the local vicinity of the follicle created by an unbalanced redox state detrimentally impacts the quality of oocytes, sperm, and embryos, hampering their cellular function, jeopardizing their viability, and that this is a fundamental underlying cause of diminished fertility with endometriosis